Integrin alpha E (ITGAE) Mouse Monoclonal Antibody [Clone ID: LF61]

CAT#: SM1800FT

Integrin alpha E (ITGAE) mouse monoclonal antibody, clone LF61, FITC


USD 190.00

5 Days*

Size
    • 25 ug

Product Images

Specifications

Product Data
Clone Name LF61
Applications FC
Recommended Dilution Flow Cytometry: Use 5 µl of neat-1/10 diluted antibody to label 106 cells in 100 µl.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Hairy cell leukaemia cells.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line.
Specificity This antibody recognizes the Human CD103 cell surface antigen. Other species not tested.
Formulation PBS
Label: FITC
State: Liquid purified IgG faction
Stabilizer: 0.5% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Absorption emission: 490 nm / 525 nm
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation FITC
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background CD103/Integrin alpha E is a new member of the integrin series of adhesion molecules containing the beta7 subunit. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20% of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs, appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis and periphery. In non-epithelial CD103+ T cells there is a bias toward expression on CD8+ cells. Integrin alpha E is a heterodimer comprising a 150kDa alpha chain and a 120kDa beta chain. Integrin alpha E is expressed by approximately 1% of peripheral blood lymphocytes, activated T lymphocytes and by hairy cell leukaemia cells. The antigen is also expressed by intraepithelial lymphocytes. It has recently been shown to be identical to the alpha E integrin.
Synonyms Integrin alpha-E, Integrin alpha-IEL, HML-1 antigen, ITGAE
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.