Granzyme B (GZMB) Mouse Monoclonal Antibody [Clone ID: GB10]

CAT#: SM1805B

Granzyme B (GZMB) mouse monoclonal antibody, clone GB10, Biotin

Specifications

Product Data

• Clone Name: GB10
• Applications: ELISA
• Recommended Dilution: ELISA: 1 µg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified human Granzyme B. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
• Specificity: This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (SM1806P) as capture reagent.
• Formulation: PBS containing 0.001% Thiomersal
  Label: Biotin
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: granzyme B
• Database Link:
  Entrez Gene 3002 Human
• Background: Ganzyme B which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.
• Synonyms: Granzyme-2, CGL1, CTSGL1, CSPB, CTLA1, CTLA-1, GRB, SECT, Fragmentin-2