CD46 Mouse Monoclonal Antibody [Clone ID: MEM-258]

CAT#: SM1819R

CD46 mouse monoclonal antibody, clone MEM-258, PE

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD46:RPE (SM1819R).

Specifications

Product Data

• Clone Name: MEM-258
• Applications: FC
• Recommended Dilution: Flow cytometry: use 10 µl of neat antibody to label 10e6 cells.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: HPB-ALL cell line
• Specificity: This antibody recognises the human CD46 cell surface antigen, a broadly expresed glycoprotein also known as membrane co-factor protein (MCP).
• Formulation: PBS with 0.09% sodium azide as preservative and 1% BSA as stabilizer
  Label: PE
  State: Lyophilized purified immunoglobulin fraction
  Label: R. Phycoerythrin
• Reconstitution Method: Restore with 1 ml distilled water.
• Purification: Protein A affinity chromatography
• Conjugation: PE
• Storage: Store at 2-8°C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD46 molecule
• Database Link:
  Entrez Gene 4179 Human
• Background: CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.
• Synonyms: TLX, MIC10