CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: BU15]
Specifications
| Product Data | |
| Clone Name | BU15 |
| Applications | FC, IHC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/10-1/50 of diluted antibody to label 10e6 cells in 100 µl. Immunoprecipitation. Immunohistochemistry on Frozen Sections: Antibody is reported to be sensitive to formaldehyde fixation and tussue prossesing. Use acetone as fixative. Not suitable for Paraffin Embedded Sections. |
| Reactivities | Human, Monkey |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody recognises the Integrin alpha X subunit. |
| Formulation | PBS buffer containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction. |
| Concentration | 1.0 mg/ml |
| Database Link | |
| Background | CD11c is a 150kD glycoprotein expressed by macrophages, monocytes, granulocytes and NK cells. The antigen is also expressed by hairy cell leukaemia cells. Ligands for CD11c are ICAM-1, iC3b, and fibrinogen. The molecule has a role in mediating adherence of granulocytes and monocytes to endothelium and fibrinogen. |
| Synonyms | ITGAX, Integrin alpha-X, Leu M5 |
| Reference Data | |
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