Mrc1 Rat Monoclonal Antibody [Clone ID: MR5D3]
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Specifications
Product Data | |
Clone Name | MR5D3 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Neat - 1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line. |
Specificity | This antibody recognises the mannose receptor, a 175kD type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: Biotin State: Liquid purified IgG |
Concentration | 0.1 mg/ml |
Purification | Affinity chromatography on Protein G |
Conjugation | Biotin |
Database Link | |
Background | CD206 is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia. |
Synonyms | Macrophage mannose receptor, CLEC13D, CLEC13DL, MRC1L1 |
Reference Data |
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