c-Myc (MYC) Mouse Monoclonal Antibody [Clone ID: 9E10]

CAT#: SM1863HRP

c-Myc (MYC) mouse monoclonal antibody, clone 9E10, HRP

Specifications

Product Data

• Clone Name: 9E10
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/100-1/500.
  Western blot: 1/100-1/500 (Non-Reducing Conditions).
  Detects a band of approximately 62kDa in Colo 320HSR cell lysates.
  Immunohistochemistry on Frozen and Paraffin Sections: This product does not require protein digestion pre-treatment of paraffin sections prior to staining and does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide sequence corresponding to the C-terminal region of Human c-myc.
• Specificity: This antibody detects the 62 kDa c-myc gene product.
  SM1863HRP may also be used to detect the commonly used c-myc 'tag'.
• Formulation: PBS, pH 7.4
  Label: HRP
  State: Liquid purified IgG fraction from tissue culture supernatant
  Stabilizer: HRP Stabilizer
  Preservative: 0.01% Thimerosal
  Label: Horseradish Peroxidase
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: HRP
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)
• Database Link:
  Entrez Gene 4609 Human
• Background: C-myc gene product is involved in the regulation of the cell cycle and cell growth. It is primarily located to the cell nucleus, but has also been shown to localised to the cytoplasm in several cell lines. Overexpression of c-myc has been reported in a wide variety of human cancers.
• Synonyms: myc tag, myc-tag, c-myc tag

Reference Data

• Protein Families: Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Pathways in cancer, Small cell lung cancer, TGF-beta signaling pathway, Thyroid cancer, Wnt signaling pathway