CD177 Mouse Monoclonal Antibody [Clone ID: MEM-166]

CAT#: SM2003F

CD177 mouse monoclonal antibody, clone MEM-166, FITC


USD 505.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name MEM-166
Applications FC
Recommended Dilution Flow cytometry (use 10 µl of neat - 1/10 diluted antibody to label 10e6 cells in 100 µl).
Reactivities Human, Rhesus Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody recognises human CD177 (neutrophil glycoprotein NB1). The neutrophil NB1 antigen is expressed by 97% of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN). Antibody reactivity and working conditions may vary between species.
Formulation PBS with 0.09% sodium azide as preservative and 1% BSA as stabelizer
Label: FITC
State: Liquid, purified immunoglobulin fraction
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Protein G affinity chromatography
Conjugation FITC
Background Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97% of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN).
Synonyms NB1, PRV1, HNA-2a, HNA2a
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.