CD226 Mouse Monoclonal Antibody [Clone ID: DX11]

CAT#: SM2023F

CD226 mouse monoclonal antibody, clone DX11, FITC

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD226:FITC.

Specifications

Product Data

• Clone Name: DX11
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1/10 - 1/20; Use 10µl of the suggested working dilution to label 1 x 10e6 cells in 100µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.
• Specificity: This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. We recommend the use of SM2023A for funtional studies.
• Formulation: PBS, pH7.4 containing 0.09% Sodium Azide and 1.0% Bovine Serum Albumin
  Label: FITC
  State: Liquid purified IgG
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: FITC
• Database Link:
  Entrez Gene 10666 Human
• Background: CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.
• Synonyms: DNAX accessory molecule 1, DNAM-1