Itga2b Rat Monoclonal Antibody [Clone ID: MWReg30]

CAT#: SM2035PT

Itga2b rat monoclonal antibody, clone MWReg30, Aff - Purified

Product Images

Staining of mouse peripheral blood with rat anti-mouse CD41 Cat.-No. SM2035P. Platelets stain strongly for CD41.

Specifications

Product Data

• Clone Name: MWReg30
• Applications: FC, IHC, IP
• Recommended Dilution: Flow cytometry (1/50-1/100): Use 10 µl to label 10e6 cells in 100 µl.
  Immunohistochemistry on Frozen Sections.
  Immunoprecipitation.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognizes the integrin alpha IIb subunit CD41.
  Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo (Nieswandt et al., 1999). SM2035A is recommended for use in functional studies.
• Formulation: PBS, containing 0.09% Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified IgG fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein G.
• Database Link:
  Entrez Gene 16399 Mouse
• Background: CD41, a ~125 kDa single pass type 1 transmembrane glycoprotein, is expressed on platelets, megakaryocytes, mast cells and hematopoietic progenitors and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.
• Synonyms: Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb