CD158 / KIR2D Mouse Monoclonal Antibody [Clone ID: NKVFS1]
Specifications
Product Data | |
Clone Name | NKVFS1 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family, CD158a, CD158b and P50.3. Clone NKVFS1 specifically recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4). The clone is reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms. We recommend the use of SM2036A for this purpose. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide, 5% Sucrose and 1% BSA Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE) |
Reconstitution Method | SM2036R: Restore with 1 ml distilled water. SM2036RT: Restore with 0.25 ml distilled water. |
Purification | Affinity Chromatography on Protein G |
Conjugation | PE |
Background | KIR2D family members are cell surface glycoproteins with two Ig domains, which are expressed on natural killer cells and some T cells. |
Synonyms | CD158a, CD158b, CD158i, KI2DL1, KIR2DL3, KIR2DS4 |
Reference Data |
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