Clec7a Rat Monoclonal Antibody [Clone ID: 2A11]

CAT#: SM2052FS

Clec7a rat monoclonal antibody, clone 2A11, FITC


USD 310.00

5 Days*

Size
    • 50 ug

Product Images

Specifications

Product Data
Clone Name 2A11
Applications FC
Recommended Dilution Flow Cytometry.
Reactivities Mouse
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1.
Specificity Recognises Murine beta-Glucan Receptor (Dectin-1).
Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells.
This antibody inhibits the binding of zymosan to macrophages via the beta-glucan receptor. The low endotoxin version SM2025LE is recommended for Functional Studies.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: FITC
State: Liquid purified IgG fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G.
Conjugation FITC
Background As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens.
Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.
Synonyms Beta-glucan receptor, BGR, CLECSF12, DECTIN1
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.