CD45 Mouse Monoclonal Antibody [Clone ID: 1.11.32]

CAT#: SM2055F

CD45 mouse monoclonal antibody, clone 1.11.32, FITC


USD 560.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 1.11.32
Applications FC
Recommended Dilution Flow Cytometry: Neat - 1/5; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Reactivities Bovine, Goat, Sheep
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Ovine efferent lymphatic duct lymphocytes
Specificity This antibody recognises the CD45 (Leucocyte common antigen), which is expressed on all ovine lymphocytes, macrophages and granulocytes.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Label: FITC
State: Liquid purified IgG
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity chromatography on Protein G
Conjugation FITC
Background CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
Synonyms Leukocyte common antigen, L-CA, PTPRC, T200, CD45RB, CD45RO, CD45RA, CD45R
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.