IL2 Rat Monoclonal Antibody [Clone ID: MQ1-17H12]

CAT#: SM2088F

IL2 rat monoclonal antibody, clone MQ1-17H12, FITC


USD 415.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name MQ1-17H12
Applications FC
Recommended Dilution Flow cytometry (neat - 1/10): Use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl. Membrane permeabilisation is required for this application.
Reactivities Human, Monkey
Host Rat
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody recognises interleukin-2 (IL-2) and may be used to detect intracellular IL-2 in flow cytometric techniques.
Formulation PBS, pH 7.4, containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Label: FITC
State: Liquid purified IgG
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Protect from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name interleukin 2
Background Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
Synonyms IL-2, TCGF
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.