Cd200r1 Rat Monoclonal Antibody [Clone ID: OX-110]

CAT#: SM2095RT

Cd200r1 rat monoclonal antibody, clone OX-110, PE

Product Images

Staining of mouse peripheral blood granulocytes with RAT ANTI MOUSE CD200R: RPE.

Specifications

Product Data

• Clone Name: OX-110
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat antibody to label 10⁶ cells in 100 µl.
  The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. This may be reduced by appropriate blocking.
  Clone OX-110 has been used successfully for the immunohistochemical detection of CD200R expressing cells on acetone fixed cryosections of murine synovial tissue (Simelyte et al. 2008).
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Fusion protein mCD200RCD4d3+4.
• Specificity: This antibody recognises CD200R.
• Formulation: PBS containing 0.09% Sodium Azide, 5% Sucrose and 1% Bovine Serum Albumin
  Label: PE
  State: Lyophilized purified IgG fraction.
  Label: R. Phycoerythrin (RPE)
  Fluorophore Excitation (nm) Emission (nm)
  PE 488nm laser 496 578
  PE 561nm laser 546 578
• Reconstitution Method: Restore with 1 ml distilled water
• Concentration: 0.1 mg/ml
• Purification: Affinity Chromatography on Protein G.
• Conjugation: PE
• Database Link:
  Entrez Gene 57781 Mouse
• Background: CD200R is a cell surface glycoprotein (also known as OX2R). Mouse CD200R is a 326 amino acid, ~48 kDa single pass type I transmembrane glycoprotein, expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (Wright et al.2003). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function (Minas and Liversidge 2006).
• Synonyms: CD200R1, CRTR2, MOX2R, OX2R, CD200 Receptor 1