CD49e / ITGA5 Rat Monoclonal Antibody [Clone ID: MFR5 (5H10)]
Specifications
Product Data | |
Clone Name | MFR5 (5H10) |
Applications | FC, IHC |
Recommended Dilution | Flow Cytometry: Use 10 µl of 1/10-1/25 diluted antibody to label 10e6 cells in 100 µl. Immunohistochemitry on Frozen Sections. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Mouse MC/9 cell line. Spleen cells from immunised Lewis rats were fused with cells of the Murine P3X63Ag8.653 |
Specificity | This antibody recognises murine integrin alpha 5 (CD49e), which associates with the beta 1 integrin (CD29) to form the fibronectin receptor CD49e/CD29 (VLA-5). Clone MFR5(5H10) has been reported to block CD49e mediated function. We recommend the use of SM2100LE for this purpose. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography on Protein G. |
Background | VLA-5 plays an important role in cell adhesion and migration and is expressed by mast cells, thymocytes, Tcells and monocytes. |
Synonyms | Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, VLA5, FNRA |
Reference Data |
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