CD52 Rat Monoclonal Antibody [Clone ID: YTH34.5]

CAT#: SM2135R

CD52 rat monoclonal antibody, clone YTH34.5, PE


USD 695.00

5 Days*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name YTH34.5
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat antibody to label 1 x 10e6 cells.
Reactivities Human, Monkey, Rhesus Monkey
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen Human lymphocytes.
Specificity This antibody CD52 antibody, clone YTH34.5 reacts with the Human CD52 antigen, also known as CAMPATH-1.
Formulation PBS
Label: PE
State: Lyophilized purified Ig fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with 1 ml distilled water.
Purification Affinity Chromatography on Protein A
Conjugation PE
Storage Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background CD52 is a small peptide that is heavily glycosylated, and attached to the cell surface membrane via a GPI link (Xia et al. 1991). The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kDa, considerably reduced following N-glycanase treatment (Rowan et al. 1998). CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies (Dearden et al. 2002; Pettitt et al. 2012).
Synonyms HE5, CDw52
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.