CD8A Mouse Monoclonal Antibody [Clone ID: CVS8]

CAT#: SM2207F

CD8A mouse monoclonal antibody, clone CVS8, FITC


USD 560.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name CVS8
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat-1/10 diluted CD8 antibody to label 106 cells in 100 µl.
Reactivities Donkey, Equine
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Equine PBMC.
Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the X63-Ag8.653 myeloma cell line.
Specificity This monoclonal CVS8 antibody recognises the Equine homologue of the Human CD8 cell surface antigen which is expressed by a subset of T lymphocytes.
A study undertaken using CVS8 to identify CD8 on several wild african equid species indicates that the CVS8 clone recognises Somali wild ass (Equus asinus) but not Grévy's Zebra (E. grevyi) or Hartmann's Mountain Zebra (E. zebra) (Ibrahim, S, 2007).
Formulation PBS
Label: FITC
State: Liquid purified IgG fraction from tissue Culture Supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation FITC
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.