Itgb1 Hamster Monoclonal Antibody [Clone ID: HM beta 1.1]

CAT#: SM2210FX

Itgb1 hamster monoclonal antibody, clone HM beta 1.1, FITC


USD 630.00

5 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name HM beta 1.1
Applications FC
Recommended Dilution Flow Cytometry: 1/25 - 1/100; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Reactivities Mouse, Rat
Host Hamster
Isotype IgG
Clonality Monoclonal
Immunogen Purified mouse VLA-4 antigen. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.
Specificity This antibody recognises the integrin beta 1 subunit (CD29). Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. WE recommend the use of SM2210LE for this purpose.
Formulation PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Label: FITC
State: Liquid purified IgG
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Purification Affinity chromatography on Protein G
Conjugation FITC
Background CD29 is a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.
Synonyms Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, ITGB1, FNRB, MDF2, MSK12
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.