NCR1 Mouse Monoclonal Antibody [Clone ID: AKS1]

CAT#: SM2227R

NCR1 mouse monoclonal antibody, clone AKS1, PE

Specifications

Product Data

• Clone Name: AKS1
• Applications: FC
• Recommended Dilution: Flow Cytometry: neat- 1/5; use 10 µl of the suggested working dilution to label 106 cells in 100 µl. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
• Reactivities: Bovine
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.
• Specificity: This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1.
  Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer
  Label: PE
  State: Lyophilised purified IgG fraction.
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1 ml distilled water
• Concentration: 0.1 mg/ml
• Purification: Affinity Chromatography on Protein G.
• Conjugation: PE
• Gene Name: -
• Database Link:
  Entrez Gene 369024 Bovine
• Background: CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.
• Synonyms: NCR1, LY94, NKp46