Fc epsilon RI (FCER1A) Mouse Monoclonal Antibody [Clone ID: 9E1]
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Specifications
Product Data | |
Clone Name | 9E1 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 106 cells in 100 µl. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0-Ag14 myeloma cell line. |
Specificity | This antibody recognizes the high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Clone 9E1 specifically recognizes the extracellular D1 domain of the Fc epsilon R1 alpha chain. |
Formulation | PBS Label: PE State: Lyophilized purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with distilled water. 1.0 ml for Cat.-No SM2251R or 0.25 ml for Cat.No SM2251RT. |
Purification | Affinity Chromatography on Protein G |
Conjugation | PE |
Database Link | |
Background | Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases. |
Synonyms | IgE Fc receptor subunit alpha, Fc-epsilon RI-alpha, FCE1A, FcERI |
Reference Data |
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