CD321 / JAM1 Rat Monoclonal Antibody [Clone ID: H202-106]

CAT#: SM2256B

CD321 / JAM1 rat monoclonal antibody, clone H202-106, Biotin

Product Images

Staining of mouse peripheral blood platelets with RAT ANTI MOUSE CD321: BIOTIN (SM2256B).

Specifications

Product Data

• Clone Name: H202-106
• Applications: FC, IHC, IP
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat-1/5 diluted antibody to label 10⁶ cells in 100 µl.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MTE1/MTE2 stromal cell lines.
  Cells from immunised Lou rats were fused with cells of the X63 mouse myeloma cell line.
• Specificity: This antibody recognizes CD321, which is also known as Junctional Adhesion Molecule 1 (JAM-1).
• Formulation: PBS, pH 7.4
  Label: Biotin
  State: Liquid purified IgG fraction from Tissue Culture Supernatant
  Stabilizer: 1% BSA
  Preservative: 0.09% Sodium Azide
• Concentration: 0.1 mg/ml
• Purification: Affinity Chromatography on Protein G
• Conjugation: Biotin
• Background: CD321 is a 32-41kD glycoprotein, which shares similarities with related proteins JAM-2 and JAM-3. CD321 is a multifunctional protein that is primarily expressed by platelets, endothelial and epithelial cells. The CD321 protein co-localises with tight junction molecules in both epithelial and endothelial cells and plays an important role in the regulation of junctional integrity and permeability. In addition, CD321 is a ligand for the integrin LFA-1 and is also involved in the transmigration of leucocytes.
• Synonyms: JAM-A, Platelet F11 receptor, F11R, JCAM, PAM1