CD321 / JAM1 Rat Monoclonal Antibody [Clone ID: H202-106]

CAT#: SM2256P

CD321 / JAM1 rat monoclonal antibody, clone H202-106, Purified

Product Images

Staining of mouse peripheral blood platelets with Rat anti Mouse CD321 antibody (SM2256P/PS/PT).

Specifications

Product Data

• Clone Name: H202-106
• Applications: FC, IHC, IP
• Recommended Dilution: Immunoprecipitation.
  Immunohistochemistry on Frozen Sections.
  Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 10e6 cells in 100 ul.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MTE1/MTE2 stromal cell lines.
• Specificity: Recognises murine CD321, which is also known as junctional adhesion molecule 1 (JAM-1).
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein G.
• Background: CD321 is a 32-41kD glycoprotein, which shares similarities with related proteins JAM-2 and JAM-3. It is a multifunctional protein that is primarily expressed by platelets, endothelial and epithelial cells. The CD321 protein co-localises with tight junction molecules in both epithelial and endothelial cells and plays an important role in the regulation of junctional integrity and permeability. In addition, CD321 is a ligand for the integrin LFA-1 and is also involved in the transmigration of leucocytes.
• Synonyms: JAM-A, Platelet F11 receptor, F11R, JCAM, PAM1