CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: Psel.KO.2.7]

CAT#: SM2261RT

CD62P (SELP) mouse monoclonal antibody, clone Psel.KO.2.7, PE

Specifications

Product Data

• Clone Name: Psel.KO.2.7
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 10⁶ cells in 100 µl.
• Reactivities: Bovine, Equine, Feline, Goat, Human, Mouse, Rat, Sheep
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: P-selectin transfected 300.19 cells.
• Specificity: This antibody recognises the CD62P cell surface antigen, a 140kD glycoprotein also known as P-Selectin.
• Formulation: PBS
  Label: PE
  State: Liquid purified IgG fraction from Tissue Culture Supernatant
  Stabilizer: 1% BSA, 5% Sucrose
  Preservative: 0.09% Sodium Azide
  Label: R. Phycoerythrin (RPE)
  Absorption emission: 488nm / 575nm
• Purification: Affinity Chromatography on Protein G
• Conjugation: PE
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: selectin P
• Database Link:
  Entrez Gene 6403 Human
• Background: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster
• Synonyms: SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3