CD244 Mouse Monoclonal Antibody [Clone ID: 2B4.69]

CAT#: SM2267R

CD244 mouse monoclonal antibody, clone 2B4.69, PE

Specifications

Product Data

• Clone Name: 2B4.69
• Applications: FC
• Recommended Dilution: Flow Cytometry: neat - 1/10; use 10 µl of the suggested working dilution to label 106 cells in 100 µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD244 Fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.
• Specificity: This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
• Formulation: PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: PE
  State: Lyophilized purified IgG
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1.0 ml distilled water
• Concentration: 0.1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: PE
• Database Link:
  Entrez Gene 51744 Human
• Background: The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
• Synonyms: NK cell type I receptor protein 2B4, NAIL, NKR2B4