Cd4 (Domain 1) Mouse Monoclonal Antibody [Clone ID: W3/25]

CAT#: SM255R

Cd4 (Domain 1) mouse monoclonal antibody, clone W3/25, PE

Specifications

Product Data

• Clone Name: W3/25
• Applications: FC
• Recommended Dilution: Flow cytometry (use 10 µl of neat - 1/10 diluted antibody to label 10e6 cells in 100 µl).
• Reactivities: Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Rat thymocyte membrane glycoproteins
• Specificity: This antibody recognises the rat CD4 cell surface glycoprotein (Domain 1), a 55 kD molecule expressed by helper T cells and weakly by monocytes.
  It inhibits proliferation and IL-2 production in the MLR reaction.
• Formulation: PBS, pH 7.4, containing 0.09% sodium azide as preservative and 1% BSA as stabilizer
  Label: PE
  State: Lyophilised purified IgG fraction
  Label: R. Phycoerythrin
• Reconstitution Method: Restore with 1 ml distilled water.
• Conjugation: PE
• Gene Name: Cd4 molecule
• Database Link:
  Entrez Gene 24932 Rat
• Background: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
• Synonyms: T-cell surface antigen T4/Leu-3