Cd8a Mouse Monoclonal Antibody [Clone ID: OX-8]

CAT#: SM259FS

Cd8a mouse monoclonal antibody, clone OX-8, FITC


USD 260.00

5 Days*

Size
    • 50 ug

Product Images

Specifications

Product Data
Clone Name OX-8
Applications FC
Recommended Dilution Flow cytometry: Use 10µl of Neat-1/10 diluted antibody to label 10e6 cells in 100 µl.
This clone has been described reacting with paraffin-embedded material following PLP Fixation (periodatelysine paraformaldehyde).
Reactivities Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Rat thymocyte membrane glycoproteins.
Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line.
Specificity This antibody recognises the CD8 alpha cell surface antigen, expressed by a subset of T lymphocytes, most thymocytes and the majority of NK cells.
Clone MRC OX-8 is suitable for use in in vitro blocking studies.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: FITC
State: Liquid purified IgG fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Ion Exchange Chromatography
Conjugation FITC
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.