CD11b Mouse Monoclonal Antibody [Clone ID: OX-42]

CAT#: SM262FS

CD11b mouse monoclonal antibody, clone OX-42, FITC


USD 260.00

5 Days*

Size
    • 50 ug

Product Images

Specifications

Product Data
Clone Name OX-42
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of Neat-1/10 diluted antibody to label 10e6 cells in 100 µl.
Clone OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde).
Functionally, clone OX-42 inhibits complement mediated rosettes. We recommend the use of SM262LE for use in functional studies.
Reactivities Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Rat resident peritoneal macrophages. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO/U myeloma cell line.
Specificity This antibody recognises the equivalent of human CD11b, the receptor for the iC3b component of complement.
The antibody also labels dendritic cells, granulocytes and microglial cells in the brain.
Formulation Phosphate Buffered Saline
Label: FITC
State: Liquid purified IgG fraction Containing 0.09% Sodium Azide and 1% BSA.
Stabilizer: Sodium Azide 0.09%
Preservative: 1% Bovine Serum Albumin
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G.
Conjugation FITC
Background The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages.
Synonyms ITGAM, CR3A, CR-3 alpha chain, Integrin alpha-M, MAC1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.