Ptprc (CD45RC) Mouse Monoclonal Antibody [Clone ID: OX-22]
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Product Data | |
Clone Name | OX-22 |
Applications | FC, IHC |
Recommended Dilution | Flow Cytometry: 1/100. Use 10µl of the suggested working dilution to label 10e6 cells in 100 µl. Immunohistochemistry on frozen sections: 1/100-1/1000. Immunohistochemsitry on paraffin sections: 1/100-1/1000. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. |
Reactivities | Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | PHA stimulated rat lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells from the NS1 mouse myeloma cell line. |
Specificity | This antibody recognizes CD45RC, the high molecular weight form of the leucocyte common antigen. |
Formulation | PBS State: Purified State: Liquid purified IgG containing 0.09% Sodium Azide Preservative: 0.09% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography on Protein G |
Gene Name | Rattus norvegicus protein tyrosine phosphatase, receptor type, C (Ptprc), transcript variant 3 |
Database Link | |
Background | The antigen is found on B cells, approximately 50% of bone marrow cells, all CD8+ve T cells, but splits CD4+ve T cells into two populations, CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like). |
Synonyms | PTPRC, Leukocyte common antigen, L-CA, T200 |
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