Icam1 Mouse Monoclonal Antibody [Clone ID: 1A29]

CAT#: SM286FX

Icam1 mouse monoclonal antibody, clone 1A29, FITC

Specifications

Product Data

• Clone Name: 1A29
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/25-1/100 diluted antibody to label 10e6 cells in 100 µl.
• Reactivities: Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Rat Ax cells (a HEV derived cell line).
• Specificity: This antibody recognises the CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1). Recent studies suggest that cross-linking of ICAM-1 using clone 1A29 induces calcium signalling. Functionally 1A29 inhibits homotypic aggregation of PHA blasts. We recommend the use of SM286LE for use in functional studies.
• Formulation: PBS, pH 7.2, containing 1% BSA as stabiliser and 0.09% Sodium Azide as preservative.
  Label: FITC
  State: Liquid purified IgG fraction
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5 mg/ml
• Purification: Affinity Chromatography on Protein G
• Conjugation: FITC
• Database Link:
  Entrez Gene 25464 Rat
• Background: CD54 is a 90kD adhesion molecule belonging to the immunoglobulin superfamily. CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and is known to play an important role in various cell-cell interactions in the immune system.
• Synonyms: ICAM-1