CD10 (MME) Mouse Monoclonal Antibody [Clone ID: MEM-78]
Specifications
Product Data | |
Clone Name | MEM-78 |
Applications | FC |
Recommended Dilution | Flow Cytometry analysis of human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | NALM-6 human pre-B cell line |
Specificity | The antibody reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein. |
Formulation | Phosphate buffered saline (PBS) solution containing 15mM sodium azide Label: PE State: Liquid Ig fraction Label: Conjugated with R-Phycoerythrin under optimum conditions |
Purification | Size-exclusion chromatography |
Conjugation | PE |
Storage | Store the antibody undiluted at 4-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Should it contain a precipitate we recommend microcentrifugation before use. |
Stability | Shelf life: one year from despatch. |
Gene Name | membrane metallo-endopeptidase |
Database Link | |
Background | CD10 (neutral endopeptidase NEP, common acute lymphocytic leukemia antigen CALLA, membrane metallo-endopeptidase MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems. |
Synonyms | MME, EPN, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase, Atriopeptidase, CALLA |
Reference Data |
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