CD2 Mouse Monoclonal Antibody [Clone ID: MEM-65]

CAT#: SM3013B

CD2 mouse monoclonal antibody, clone MEM-65, Biotin


USD 270.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name MEM-65
Applications FC
Recommended Dilution Indirect immunofluorescence analysis by Flow cytometry: 1:1000.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human peripheral T cells
Specificity This antibody recognizes an unique epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells; also expressed by all thymocytes.
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Label: Biotin
State: Liquid purified Ig fraction
Label: Conjugated with -LC-NHS under optimum conditions. The reagent is free of unconjugated biotin
Concentration lot specific
Conjugation Biotin
Storage Store the antibody undiluted at 2 - 8 °C. DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD2 molecule (CD2), transcript variant 2
Background CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Synonyms SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Hematopoietic cell lineage

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.