CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: MEM-06]

CAT#: SM3021APC

CD41 (ITGA2B) mouse monoclonal antibody, clone MEM-06, APC


USD 300.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name MEM-06
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 µl reagent/100 µl of whole blood or 10e6 cells in a suspension. 
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Leukocytes of patient suffering from LGL-type leukaemia
Specificity This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIbalpha (heavy chain: 120 kDa) and GPIIbbeta (light chain: 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Formulation PBS containing 15 mM Sodium Azide as preservative
Label: APC
State: Liquid purified Ig fraction
Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation APC
Storage Store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name integrin subunit alpha 2b
Background CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Synonyms Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.