CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: MEM-06]

CAT#: SM3021PP

CD41 (ITGA2B) mouse monoclonal antibody, clone MEM-06, PerCP


USD 300.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name MEM-06
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Leukocytes of patient suffering from LGL-type leukaemia
Specificity This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Formulation Phosphate buffered saline (PBS)
Label: PerCP
State: Liquid purified Ig fraction
Preservative: 15 mM sodium azide
Label: Conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation PerCP
Storage Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name integrin subunit alpha 2b
Background CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Synonyms Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.