CD55 / DAF Mouse Monoclonal Antibody [Clone ID: MEM-118]

CAT#: SM3030F

CD55 / DAF mouse monoclonal antibody, clone MEM-118, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name MEM-118
Applications FC
Recommended Dilution Flow Cytometry: Analysis of Human blood cells using 20 μl reagent/100 μl of whole blood or 106 cells in a suspension.
Reactivities Human, Primate
Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen HPB-ALL human T cell line
Specificity The antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.
Formulation Tris buffered saline (TBS)
Label: FITC
State: Liquid purified Ig fraction
Preservative: 15 mM sodium azide
Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation FITC
Background CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.