CD55 Mouse Monoclonal Antibody [Clone ID: MEM-118]

CAT#: SM3030PE

CD55 mouse monoclonal antibody, clone MEM-118, PE

Product Images

Surface staining of human peripheral blood cells with anti-CD55 (MEM-118) PE.

Specifications

Product Data

• Clone Name: MEM-118
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
• Reactivities: Human, Primate
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: HPB-ALL human T cell line
• Specificity: This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.
• Formulation: Tris buffered saline (TBS) solution containing 15 mM sodium azide
  Label: PE
  State: Liquid purified Ig fraction
  Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
• Conjugation: PE
• Storage: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens CD55 molecule (Cromer blood group) (CD55), transcript variant 1
• Database Link:
  Entrez Gene 1604 Human
• Background: CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
• Synonyms: CR; CROM; DAF; TC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades, Hematopoietic cell lineage, Viral myocarditis