LFA3 (CD58) Mouse Monoclonal Antibody [Clone ID: MEM-63]

CAT#: SM3032AC

LFA3 (CD58) mouse monoclonal antibody, clone MEM-63, APC


USD 300.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name MEM-63
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human, Porcine
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen NALM-6 human pre-B cell line
Specificity This antibody reacts with CD58 (LFA-3), a 40-70 kDa glycoprotein distributed over many tissues, leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts.
Formulation Tris buffered saline (TBS) solution containing 15 mM sodium azide
Label: APC
State: Liquid purified Ig fraction
Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation APC
Storage Store undiluted at 2-8°C. DO NOT FREEZE!
This products is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
Synonyms Ag3, LFA-3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.