CD59 Mouse Monoclonal Antibody [Clone ID: MEM-43/5]

CAT#: SM3033R

CD59 mouse monoclonal antibody, clone MEM-43/5, PE

Specifications

Product Data

• Clone Name: MEM-43/5
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of Neat antibody to label 10e6 cells in 100 µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: This antibody reacts with a PI-linked glycoprotein, Mw 18-20kD found on all types of leucocytes including platelets. The antigen is expressed on many haemopoietic and non-haemopoietic cells.
• Formulation: PBS containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer
  Label: PE
  State: Lyophilized purified IgG fraction
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 0.25 ml distilled water.
• Purification: Affinity Chromatography on Protein A
• Conjugation: PE
• Storage: Store the antibody undiluted Prior to and after reconstitution at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 966 Human
• Background: CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
• Synonyms: MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21, MACIF, MAC-IP, MIRL, HRF20, HRF-20