CD63 Mouse Monoclonal Antibody [Clone ID: MEM-259]

CAT#: SM3035F

CD63 mouse monoclonal antibody, clone MEM-259, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name MEM-259
Applications FC, IF
Recommended Dilution Flow Cytometry: analysis of Human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. 
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen HPB-ALL T cell line
Specificity This antibody reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.
Formulation Phosphate Buffered Saline (PBS)
Label: FITC
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free BSA
Preservative: 15 mM Sodium Azide
Label: Fluorescein Isothiocyanate.
The reagent is free of unconjugated and adjusted for direct use
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C. 
DO NOT FREEZE! 
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.
Synonyms OMA81H, Granulophysin, Tetraspanin-30, MLA1, TSPAN30, ME491
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.