CD9 Mouse Monoclonal Antibody [Clone ID: IVA50]

CAT#: SM3040P

CD9 mouse monoclonal antibody, clone IVA50, Purified

Product Images

Immunoprecipitation of human CD9 from the biotin-labeled human platelets lysates. Lane 1: immunoprecipitation with anti-CD9 (IVA50). Lane 2: immunoprecipitation with anti-human CD9 control antibody. Lane 3: immunoprecipitation with negative control.

Specifications

Product Data

• Clone Name: IVA50
• Applications: FC, FN, IP, WB
• Recommended Dilution: Flow cytometry.
  Immunoprecipitation.
  Western blotting.
  Functional application (the antibody activates bovine thrombocytes).
• Reactivities: Bovine
• Host: Mouse
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Bovine thrombocytes
• Specificity: Clone IVA50 reacts with CD9 antigen, a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
• Formulation: PBS, pH 7.4, with 15 mM sodium azide as preservative
  State: Purified
  State: Liquid Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Protein A affinity chromatography ( > 95% by SDS-PAGE)
• Gene Name: -
• Database Link:
  Entrez Gene 280746 Bovine
• Background: CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
• Synonyms: MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen