CD99 (CD99R Isoform) Mouse Monoclonal Antibody [Clone ID: MEM-131]
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Specifications
Product Data | |
Clone Name | MEM-131 |
Applications | FC, IP, WB |
Recommended Dilution | Flow Cytometry. Immunoprecipitation. Western Blotting under non reducing conditions. Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml, Positive tissue: thymic lymphocytes |
Reactivities | Human |
Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Immunogen | HPB-ALL human peripheral blood leukemia T-cell line |
Specificity | The antibody reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes. |
Formulation | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Precipitation methods; purity: > 95% (by SDS-PAGE) |
Storage | Store the antibody at 2 - 8 °C. Do not freeze. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells. |
Synonyms | E2 antigen, 12E7, MIC2X, MIC2Y |
Reference Data |
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