CD99 (CD99R Isoform) Mouse Monoclonal Antibody [Clone ID: MEM-131]
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Specifications
Product Data | |
Clone Name | MEM-131 |
Applications | FC |
Recommended Dilution | Flow Cytometry analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 10e6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Reactivities | Human |
Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Immunogen | HPB-ALL human peripheral blood leukemia T-cell line |
Specificity | The antibody reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes. |
Formulation | Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent Label: PE State: Liquid purified Ig fraction Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use |
Conjugation | PE |
Storage | Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens CD99 molecule (CD99), transcript variant 2 |
Database Link | |
Background | CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells. |
Synonyms | E2 antigen, 12E7, MIC2X, MIC2Y |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration |
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