Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: A67-B/E3]

CAT#: SM3072B

Prostate Specific Antigen (KLK3) mouse monoclonal antibody, clone A67-B/E3, Biotin

Product Images

Immunohistochemistry staining of prostate (paraffin-embedded sections) with anti-human Prostate-specific antigen (A67-B/E3).

Specifications

Product Data

• Clone Name: A67-B/E3
• Applications: ELISA, IHC, WB
• Recommended Dilution: Western blot: 1:1000.
  ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: 30 KDa protein fraction prepared from human seminal plasma
• Specificity: This antibody reacts with prostate-specific antigen (PSA),a protein produced by normal prostate cells. The highest amounts of PSA are found in the seminal fluid.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  Label: Biotin
  State: Liquid purified Ig fraction
  Label: Conjugated with -LC-NHS under optimum conditions. The reagent is free of unconjugated biotin
• Concentration: lot specific
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2 - 8 °C. DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens kallikrein related peptidase 3 (KLK3), transcript variant 3
• Database Link:
  Entrez Gene 354 Human
• Background: Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid; some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer.
• Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Pathways in cancer, Prostate cancer