TRIM (TRAT1) (29-186) Mouse Monoclonal Antibody [Clone ID: TRIM-04]

CAT#: SM3077P

TRIM (TRAT1) (29-186) mouse monoclonal antibody, clone TRIM-04, Purified

Product Images

Western blot of human Jurkat T cell line lysate (1% laurylmaltoside); non-reduced sample, immunostained by mAbTRIM-04andgoat anti-mouse IgG (H+L)-HRPconjugate.

Specifications

Product Data

• Clone Name: TRIM-04
• Applications: FC, IP, WB
• Recommended Dilution: Immunoprecipitation.
  Western Blot (Non reducing conditions).
  Flow Cytometry (Intracellular staining).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant intracellular domain (aa 29-186) of Human TRIM
• Specificity: The antibody TRIM-04 reacts with T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
• Formulation: PBS, pH~7.4
  State: Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein A
• Database Link:
  Entrez Gene 50852 Human
• Background: TRIM (T cell receptor-interacting molecule) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
• Synonyms: TCRIM