CD52 Mouse Monoclonal Antibody [Clone ID: HI186]

CAT#: SM3081R

CD52 mouse monoclonal antibody, clone HI186, PE


USD 300.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name HI186
Applications FC
Recommended Dilution Flow Cytometry: Use 20 µl to label 106 cells in a suspension or 100 µl whole blood. 
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human tonsil.
Specificity This antibody reacts with Human  CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, Monocytes/Macrophages and in male reproductive tract.
Formulation PBS
Label: PE
State: Liquid purified IgG fraction
Stabilizer: 0.2% (w/v) high-grade protease free BSA
Preservative: 15 mM Sodium Azide
Label: Conjugated with R-Phycoerythrin under optimum conditions
Purification Size-Exclusion Chromatography
Conjugation PE
Storage Store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background CD52 is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
Synonyms HE5, CDw52
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.