CD38 Mouse Monoclonal Antibody [Clone ID: HIT2]

CAT#: SM3083R

CD38 mouse monoclonal antibody, clone HIT2, PE

Product Images

Surface staining of PHA stimulated human peripheral blood lymphocytes with anti-human CD38 (HIT2) PE.

Specifications

Product Data

• Clone Name: HIT2
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of Human blood cells using 20 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human thymocytes in foetus
• Specificity: This antibody reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.
• Formulation: Phosphate buffered saline (PBS) solution containing 15mM sodium azide
  Label: PE
  State: Liquid purified Ig fraction
  Label: Conjugated with R-Phycoerythrin under optimum conditions
• Purification: Size-Exclusion Chromatography
• Conjugation: PE
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 952 Human
• Background: CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.
• Synonyms: cADPr hydrolase 1, T10