CD10 (MME) Mouse Monoclonal Antibody [Clone ID: LT10]

CAT#: SM3139F

CD10 (MME) mouse monoclonal antibody, clone LT10, FITC

Product Images

Surface staining of human peripheral blood cells with anti-CD10 (LT10) FITC.

Specifications

Product Data

• Clone Name: LT10
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 20 µl reagent / 100 µl whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)
• Specificity: The antibody reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
• Formulation: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
  Label: FITC
  State: Liquid purified Ig fraction
  Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated and adjusted for direct use
• Conjugation: FITC
• Storage: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: membrane metallo-endopeptidase
• Database Link:
  Entrez Gene 4311 Human
• Background: CD10 (neutral endopeptidase NEP, common acute lymphocytic leukemia antigen CALLA, membrane metallo-endopeptidase MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
• Synonyms: MME, EPN, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase, Atriopeptidase, CALLA