CD8A Mouse Monoclonal Antibody [Clone ID: vpg9]

CAT#: SM424R

CD8A mouse monoclonal antibody, clone vpg9, PE

Specifications

Product Data

• Clone Name: vpg9
• Applications: FC
• Recommended Dilution: Flow Cytometry.
• Reactivities: Feline
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Feline thymocytes. Spleen cells from immunised BALB/c were fused with cells of the NSO mouse myeloma cell line
• Specificity: This antibody recognises the homologue of human CD8. Clone vpg 9 specifically recognises an epitope associated with the alpha/beta complex of the CD8 heterodimer.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: PE
  State: Lyophilized purified IgG
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1 ml distilled water
• Conjugation: PE
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
• Synonyms: CD8 alpha chain, CD8A, MAL