CD8A Mouse Monoclonal Antibody [Clone ID: MIL-12]
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Specifications
Product Data | |
Clone Name | MIL-12 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10µl of Neat antibody to label 10e6 cells in 100 µl. |
Reactivities | Porcine |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Porcine mesenteric lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the P3 - X63 - Ag.653 myeloma cell line. |
Specificity | This antibody recognises a subset of T cells. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: FITC State: Liquid purified IgG fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | 0.1 mg/ml |
Purification | Affinity Chromatography on Protein G |
Conjugation | FITC |
Gene Name | - |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Synonyms | CD8 alpha chain, CD8A, MAL |
Reference Data |
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