CD4 Mouse Monoclonal Antibody [Clone ID: CVS4]
Specifications
Product Data | |
Clone Name | CVS4 |
Applications | FC |
Recommended Dilution | Flow cytometry: Neat-1/10, use 10µl of this working dilution to label 10e6 cells in 100µl. |
Reactivities | Equine |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Equine thymocytes |
Specificity | This anitbody reacts with T-helper cells, it recognises a 58kDa cell surface glycoprotein that is primarily expressed on a subpopulation of equine T lymphocytes and considered to be the equine homologue of human CD4. |
Formulation | Containing 0.09% Sodium azide and 1% BSA Label: FITC State: Purified State: Liquid purified IgG Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | 0.1 mg/ml |
Purification | Affinity chromatography on Protein G from tissue culture supernatant |
Conjugation | FITC |
Background | CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. |
Synonyms | T-cell surface antigen T4/Leu-3 |
Reference Data |
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