CD44 Mouse Monoclonal Antibody [Clone ID: CVS18]

CAT#: SM502R

CD44 mouse monoclonal antibody, clone CVS18, PE, Purified

Specifications

Product Data

• Clone Name: CVS18
• Applications: FC
• Recommended Dilution: Flow cytometry: Neat, use 10µl to label 10⁶ cells in 100µl.
• Reactivities: Equine
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Equine leucocytes
• Specificity: Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker.
• Formulation: 0.09% Sodium azide, 1% BSA and 5% Sucrose
  Label: PE
  State: Purified
  State: Lyophilised purified IgG
  Label: R. Phycoerythrin
• Reconstitution Method: Restore with 1.0 ml distilled water.
• Purification: Affinity chromatography on Protein G
• Conjugation: PE
• Background: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
• Synonyms: LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1